Coronavirus Disease (COVID-19)

Discussion in 'General OT' started by imart, Jan 28, 2020.

  1. Invisigoth

    Invisigoth Member

    Joined:
    Nov 9, 2020
    Messages:
    77
    Likes Received:
    33
    Location:
    RV
    I would let everyone on this thread go ahead of me.

    I will wait to be the 23 millionth Pinoy to get it. Ideally I'd be the 88th million.

    Its just me I'm not convincing anybody to do the same.

    For reasons of politics I hope the vaccine gets distributed after 15 months from today.

    I want a change from govt that imposed the longest non-stop quarantine in the world.

    Someone who is data driven rather than politics driven.
     
    Godfather, wulf and Nisroc88 like this.
  2. raypin

    raypin PhilMUG Addict Member

    Joined:
    Jun 8, 2008
    Messages:
    13,850
    Likes Received:
    6,887
    Sir iAco likes this.
  3. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    Two stillborn babies test positive for COVID-19 in Israel
    By Lee Brown
    Two stillborn babies test positive for COVID-19 in Israel (nypost.com)
    February 28, 2021 | 10:33am | Updated

    [​IMG]

    Two stillborn babies in Israel from mothers infected with COVID-19 have also tested positive for the coronavirus — with at least one of the deaths blamed on the contagion, according to a report.

    A woman in her 36th week of pregnancy lost her unborn child at the Meir Medical Center in Kfar Saba Saturday after falling sick with COVID-19, the Times of Israel said.

    Tests showed that the fetus was also infected, but the hospital did not immediately blame the pandemic for the death.

    However, it was declared the likely cause of death in an almost identical case last week when a 29-year-old woman lost her child in the 25th week of pregnancy in Ashdod, the outlet said.

    “The fetus was infected through the placenta and with a very high degree of certainty, [we can say] died due to coronavirus,” Dr. Tal Brosh, head of the Infectious Disease Department at the Assuta Hospital, told Ynet news.

    It was the first case of its kind reported in Israel, although others have previously been noted in Brazil, the report said.

    “This is a rare occurrence because a baby is usually infected with coronavirus after birth, as a result of contact with the mother,” said Dr. Yossi Tobin, the director of the maternity ward at the hospital.

    “The fact that we were able to find out that they were already positive in the womb indicates a high probability that [the fetus] died as a result of coronavirus.”

    The US Centers for Disease Control and Prevention (CDC) recommends that pregnant women get vaccinated, but mostly listing health dangers to the mother rather than their unborn children.

    “Pregnant people with COVID-19 might be at increased risk of adverse pregnancy outcomes, such as preterm birth,” the CDC warned.

    Two stillborn babies test positive for COVID-19 in Israel (nypost.com)
     
  4. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    You will have a long wait. Moderna and Pfizer are in limited supply. They are being used in the U.S. and given to eligible groups in priority order.

    Philippines receives Chinese vaccine, but Duterte prefers another brand
    First shipment of COVID-19 vaccine arrives in Philippines

    Philippines receives Chinese vaccine, but Duterte prefers another brand (yahoo.com)

    I'll have what DU30 is having.

    [​IMG]
     
    Godfather likes this.
  5. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    A Covid Vaccine Side Effect, Enlarged Lymph Nodes, Can Be Mistaken for Cancer
    The condition is becoming more common as immunization rates increase. Experts are suggesting ways to ease patients’ fears and avoid needless testing.

    Source: A Covid Vaccine Side Effect, Enlarged Lymph Nodes, Can Be Mistaken for Cancer - The New York Times (nytimes.com)
    [​IMG]
    Covid-19 vaccinations at the Community Center in Rohnert Park, Calif. Swelling of lymph nodes in the armpit became a recognized side effect in the trials of the Moderna and Pfizer-BioNTech vaccines.Credit...Jim Wilson/The New York Times
    By Denise Grady

    Coronavirus vaccinations can cause enlarged lymph nodes in the armpit or near the collarbone, which may be mistaken for a sign of cancer.

    As vaccines are rolled out across the country, doctors are seeing more and more of these swollen nodes in recently immunized people, and medical journals have begun publishing reports aimed at allaying fears and helping patients avoid needless testing for a harmless condition that will go away in a few weeks.

    The swelling is a normal reaction by the immune system to the vaccine, and occurs on the same side as the arm where the shot was given. It can also occur after other vaccinations, including those for flu and the human papillomavirus (HPV). Patients may or may not notice it. But the enlarged lymph nodes show up as white blobs on mammograms and chest scans, resembling images that can indicate the spread of cancer from a tumor in the breast or elsewhere in the body.

    “I am particularly eager to get the word out to all the patients undergoing surveillance after successful prior treatment of cancer,” said Dr. Constance D. Lehman, an author of two journal articles on the problem and the chief of breast imaging at the Massachusetts General Hospital. “I can’t imagine the anxiety of getting the scan and hearing, ‘We found a node that is large. We don’t think it’s cancer but can’t tell,’ or worse, ‘We think it might be cancer.’”

    The swelling in the armpit was a recognized side effect in the large trials of the Moderna and Pfizer-BioNTech vaccines. In Moderna’s study, 11.6 percent of patients reported swollen lymph nodes after the first dose, and 16 percent after the second dose. Pfizer-BioNTech appeared to have a lower incidence, with 0.3 percent of patients reporting it. But those figures reflect only what patients and their doctors noticed, and radiologists say that the real rate is probably higher, and that many more cases are likely to show up on imaging like mammograms, or M.R.I.s or CT scans.

    The condition was not listed among the reported side effects in a briefing document from the Food and Drug Administration about the Johnson & Johnson Covid vaccine. On Saturday, the agency authorized the company’s vaccine for emergency use.

    [​IMG]
    Image
    The image on the left shows a 41-year-old man’s right shoulder, with arrows pointing to normal-size lymph nodes in the armpit. The image on the right shows swelling in his left arm (dashed yellow arrow) and enlarged lymph nodes (yellow arrows) in his armpit. He had received a Covid vaccination four days earlier. Although he previously had cancer, the swollen nodes were thought to be caused by the vaccine.Credit...Özütemiz et al., Radiology 2021
    Dr. Lehman said it was important for imaging centers to ask patients if they have had Covid inoculations and to record the date of the shot and the arm in which it was given.

    Her clinic includes this advisory in a letter to patients whose screenings detect swelling but no other abnormalities: “The lymph nodes in your armpit area that we see on your mammogram are larger on the side where you had your recent Covid-19 vaccine. Enlarged lymph nodes are common after the Covid-19 vaccine and are your body’s normal reaction to the vaccine. However, if you feel a lump in your armpit that lasts for more than six weeks after your vaccination, you should let your health care provider know.”

    One way people could avoid the problem would be to postpone routine mammograms and other imaging for at least six weeks after the last dose of vaccine, according to an article by an expert panel in the journal Radiology, published on Wednesday.

    A professional group, the Society of Breast Imaging, offers similar advice: “If possible, and when it does not unduly delay care, consider scheduling screening exams prior to the first dose of a Covid-19 vaccination or 4-6 weeks following the second dose of a Covid-19 vaccination.”

    But the expert panel also cautioned that nonroutine imaging, needed to help deal with an illness or other symptoms that might indicate cancer, should not be delayed. Nor should immunization.

    People who have cancer are generally advised to be vaccinated against the coronavirus, particularly because they are at higher risk of dying from Covid than the general population. But some cancer treatments may interfere with the body’s ability to respond fully to the vaccine, and the American Cancer Society advises patients to consult with their oncologists about vaccination.

    In recently vaccinated people who have cancer and develop enlarged lymph nodes, it may be necessary to perform more tests, including a biopsy of the nodes, Dr. Lehman said.

    She described one patient with a newly diagnosed breast tumor who had swollen lymph nodes on the same side, and had recently received a Covid shot in the arm on that side.

    A biopsy was performed, an important step to determine whether there were malignant cells in the nodes that would then help decide a course of treatment. It was negative for cancer. The vaccine had most likely caused the swelling.

    In another case, a woman who previously had cancer in her right breast had a routine mammogram that showed an enlarged lymph node in her left armpit, and no other abnormality. She’d recently received a Covid vaccination in the left arm. Doctors determined that no more tests would be needed unless the swollen nodes lasted more than six weeks.

    In a man with a history of bone cancer, a chest CT scan performed as part of a follow-up found swollen lymph nodes in one armpit — on the side where he’d recently had a Covid inoculation. Nothing else was wrong and no further tests were needed. The same decision was made for similar findings in a recently vaccinated man who had a chest CT to screen for lung cancer, and in a woman with a history of melanoma.

    For patients undergoing treatment for cancer in one breast, Dr. Lehman said, the Covid shot should be given in the arm on the other side. The vaccine can also be injected into the thigh to prevent any issues with lymph node swelling.

    “This could really impact a lot of people if we don’t start recording vaccination status immediately at imaging centers,” Dr. Lehman said. “I also want cancer patients to know they can get the vaccine on the opposite side or even the leg to avoid confusion.”

    The Coronavirus Vaccine Rollout
    The vaccines are quite safe, and side effects are rare, the C.D.C. reports.
    Feb. 19, 2021

    What the Vaccine Side Effects Feel Like, According to Those Who’ve Gotten It
    Dec. 28, 2020


    A Covid Vaccine Side Effect, Enlarged Lymph Nodes, Can Be Mistaken for Cancer - The New York Times (nytimes.com)

    Denise Grady has been a science reporter for The Times since 1998. She wrote “Deadly Invaders,” a book about emerging viruses. nytDeniseGrady

    The Coronavirus Outbreak

    SOURCE: The vaccines are quite safe, and side effects are rare, the C.D.C. reports. - The New York Times (nytimes.com)
     
  6. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    This important study has flown under the radar:
    • no live virus shedding beyond day 9 of illness
    • viral load in the upper respiratory tract peaks in the first week of illness
    SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis

    Muge Cevik, MRCP Matthew Tate, MRCP Ollie Lloyd, MRCP Alberto Enrico Maraolo, MD Jenna Schafers, MRCP Antonia Ho, PhD

    Published:November 19, 2020

    SOURCE: thelancet.com

    Findings

    79 studies (5340 individuals) on SARS-CoV-2, eight studies (1858 individuals) on SARS-CoV, and 11 studies (799 individuals) on MERS-CoV were included. Mean duration of SARS-CoV-2 RNA shedding was 17·0 days (95% CI 15·5–18·6; 43 studies, 3229 individuals) in upper respiratory tract, 14·6 days (9·3–20·0; seven studies, 260 individuals) in lower respiratory tract, 17·2 days (14·4–20·1; 13 studies, 586 individuals) in stool, and 16·6 days (3·6–29·7; two studies, 108 individuals) in serum samples. Maximum shedding duration was 83 days in the upper respiratory tract, 59 days in the lower respiratory tract, 126 days in stools, and 60 days in serum. Pooled mean SARS-CoV-2 shedding duration was positively associated with age (slope 0·304 [95% CI 0·115–0·493]; p=0·0016). No study detected live virus beyond day 9 of illness, despite persistently high viral loads, which were inferred from cycle threshold values. SARS-CoV-2 viral load in the upper respiratory tract appeared to peak in the first week of illness, whereas that of SARS-CoV peaked at days 10–14 and that of MERS-CoV peaked at days 7–10.

    Interpretation

    Although SARS-CoV-2 RNA shedding in respiratory and stool samples can be prolonged, duration of viable virus is relatively short-lived. SARS-CoV-2 titres in the upper respiratory tract peak in the first week of illness. Early case finding and isolation, and public education on the spectrum of illness and period of infectiousness are key to the effective containment of SARS-CoV-2.

    SOURCE:
    SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis - The Lancet Microbe
     
    raypin likes this.
  7. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    [​IMG]
    New Orleans Archdiocese Asks Catholics to Avoid Johnson & Johnson COVID Vaccine
    Brittany Bernstein
    Mon, March 1, 2021, 3:46 PM
    What you need to know about Johnson & Johnson’s COVID-19 vaccine (yahoo.com)
    [​IMG]
    The Catholic Archdiocese of New Orleans is asking Catholics to avoid the recently-approved Johnson & Johnson COVID-19 vaccine, which it says is “morally compromised” by its “extensive use of abortion-derived cell lines.”

    In a statement on Friday, the archdiocese noted that while deciding whether to receive the vaccine is an individual choice, that “the latest vaccine from Janssen/Johnson & Johnson is morally compromised as it uses the abortion-derived cell line in development and production of the vaccine as well as the testing.”

    While a number of COVID-19 vaccine manufacturers have used cells originally derived from an aborted fetus in the 1970s, the archdiocese argues that Johnson & Johnson “extensive use” is worse than that of Moderna and Pfizer-BioNTech vaccines, which used the cells lines only to test their vaccines, according to Religion News Service. This makes the “connection to abortion … extremely remote,” in the Moderna and Pfizer vaccines, the statement argues, recommending that Catholics choose one of those instead, if provided a choice.

    While the archdiocese claims the decision is in line with guidance from the Vatican, the U.S. Conference of Catholic Bishops and the National Catholic Bioethics Center, none of the three have issued statements denouncing the new vaccine.

    In December, the Vatican issued general guidelines regarding vaccines in which the Holy See said it was “morally acceptable” for Catholics to receive shots that used the HEK293 cells for research. While the HEK293 cells are reportedly originated from an aborted fetus from the 1970s, ethicists have said that the cells and similar cell lines are clones and not the original fetal tissue.

    The Vatican has made the Pfizer-BioNTech vaccine available for all Vatican City residents. Pope Francis reportedly received the shot in January.

    The Archdiocese of New Orleans’ statement comes after leaders of the USCCB and leaders from other religious organizations sent a letter to the commissioner of the U.S. Food and Drug Administration last spring regarding ethical concerns over the COVID-19 vaccines.

    “We are aware that, among the dozens of vaccines currently in development, some are being produced using old cell lines that were created from the cells of aborted babies,” the letter read. “For example, Janssen Pharmaceuticals, Inc. has a substantial contract from the U.S. Department of Health and Human Services (HHS) and is working on a vaccine that is being produced using one of these ethically problematic cell lines.”

    However, a USCCB memo written by Bishop Kevin C. Rhoades of Fort Wayne-South Bend, who chairs the USCCB’s Committee on Doctrine, and Archbishop Joseph F. Naumann of Kansas City, who chairs the organization’s Committee on Pro-Life Activities, argued that the vaccines are moral.

    More from National Review
    What you need to know about Johnson & Johnson’s COVID-19 vaccine (yahoo.com)
     
    #2547 Sir iAco, Mar 2, 2021
    Last edited: Mar 2, 2021
  8. wuyckie

    wuyckie Member

    Joined:
    Sep 6, 2008
    Messages:
    368
    Likes Received:
    16
    Location:
    Manila
  9. sandybridge_guy

    sandybridge_guy PhilMUG Addict Member

    Joined:
    Mar 15, 2011
    Messages:
    1,740
    Likes Received:
    1,238
    Gender:
    Male
    Location:
    Edmonton, Alberta Canada
    Here it will take up to end of 3rd Q before the common folk can get innoculated.

    At least we have a good 9 months to observe side-effects (if there is) to first recipients.
     
    Sir iAco likes this.
  10. dasaint

    dasaint PhilMUG Addict Member

    Joined:
    Aug 23, 2005
    Messages:
    2,076
    Likes Received:
    427
    Location:
    Vietnam
    my slot for the sinovac has been confirmed I am taking it . politics aside I read through the data and advised by 3 medical doctors include one who is a dean in one of the oldest medical school in the Philippines all friends . I am taking it.
     
    Sir iAco and Shinahashirome like this.
  11. Adarna

    Adarna Well-Known Member

    Joined:
    Dec 27, 2014
    Messages:
    778
    Likes Received:
    482
    Pls get back to us by next week or next month. I'd like to get your take on it.
     
    dasaint and Sir iAco like this.
  12. raypin

    raypin PhilMUG Addict Member

    Joined:
    Jun 8, 2008
    Messages:
    13,850
    Likes Received:
    6,887
    Mm...nothing to do with anti-China politics but the main objection to Sinovac seems to stem from the media-reported much lower efficacy rate of Sinovac of 50% plus percent vs. the 94 to 95% efficacy of the US vaccines from Moderna and Pfizer BioNtech. Masyadong malayo yung difference. It appears that the US vaccines are far more effective and that extra margin affords one far more protection from developing severe symptoms that will require hospitalization.

    The government says Sinovac passed the threshold of 50% as set by the WHO in order for a vaccine to be considered as viable for mass innoculation.

    Now, as with any vaccine, it is an individual decision to choose whether to vaccinate or not to vaccinate.

    All Covid vaccines, at this point, are on emergency authorization use worldwide, meaning it will take much more time to fully establish its actual efficacy and safety. So, there are real risks. The way I see it is: are the risks of developing serious side effects from vaccination greater or lesser than the risk of being infected with the Covid 19 virus and develop serious symptoms that may result in death? It also depends on your work or profession. If you are exposed to people or strangers on a day to day basis, it may be advisable to get the vaccine that is now available and not wait (sooner is better than later). With the impending relaxation of quarantine rules (example: no more testing for travel etc.), the safety net will be removed and this policy decision will probably (high probability) result in a spike in infection rate. So, vaccination takes on a more important role in mitigating this impending public health disaster and the best vaccine is the one that you can get today. Some protection is better than no protection.
     
    #2552 raypin, Mar 3, 2021
    Last edited: Mar 3, 2021
  13. ice

    ice PhilMUG Addict Member

    Joined:
    Dec 13, 2007
    Messages:
    10,053
    Likes Received:
    2,046
    Location:
    NCR
    AstraZeneca, Sputnik vaccines face hurdles if COVID-19 shots become annual affair | CNA

     
  14. Shinahashirome

    Shinahashirome Active Member

    Joined:
    Feb 1, 2013
    Messages:
    379
    Likes Received:
    136
    Gender:
    Male
    Location:
    Las Piñas, Manila
    Based on my research and from doctor friends, the 55% efficacy rate of sinovac is for the prevention of mild symptoms (colds, fever) compared to other vaccines that range from 90% up to 96% in 2 doses. But all vaccines have a 100% efficacy rate in preventing severe (life-threatening) symptoms including sinovac. The only caveat is that you need 2 shots for these vaccines except for the J&J vaccine.
     
    Godfather and raypin like this.
  15. ice

    ice PhilMUG Addict Member

    Joined:
    Dec 13, 2007
    Messages:
    10,053
    Likes Received:
    2,046
    Location:
    NCR
    Just updated my "location" as I'm now officially in Manila

    Few things I've noticed with Manila's "new normal" (compared to Singapore)

    • Tracing Apps/Forms are NOT unified and NOT fully enforced (guard won't even check if you completed the form)
    • Some food courts/fast food allow entry of customers even if there are no seats available!
    • Went to Starbucks on my first day out of quarantine and guard told me its "clean as you go" -> I find this crazy weird as in Singapore, resto staff will clean and sanitize the table you used before allowing the next person to use the table
    • Hand contact with people still cannot be avoided -> parking fees
    • Haircut is done without masks!
    • Pinoys have learned to eat while wearing a mask and face shield!
    • Some establishments started a new normal but have not updated their office! -> I went for a medical check yesterday and the clinic required guests to change clothes before entering... but the only changing room they have is the men's/ladies' room!
     
    raypin likes this.
  16. shifty_md

    shifty_md Well-Known Member

    Joined:
    Jul 27, 2013
    Messages:
    907
    Likes Received:
    356
    Location:
    Manila
    Vaccines have started to roll out on our training Hospital. They have no political color, in fact right now it shouldn’t have any Nationality. We all are fighting a common enemy. Hence given the urgency, any armament, even from a Regime I despise for laying claim to our Sovereignty, is one positive step towards a shared victory for humanity. Thank you, Xi Jinping but we still own WPS.
     
  17. Nisroc88

    Nisroc88 Active Member

    Joined:
    Jun 17, 2020
    Messages:
    132
    Likes Received:
    54
    Gender:
    Male
    Location:
    philippines
    I’m just a family man and not a medical professional but over at our multitool forum, we have a saying that the best multitool is the one you have on you right now - whether it’s Swiss, American or Chinese. I guess the same thing can be said about face masks or face shields. I mean I don’t even remember the brand of flu vaccine we get.

    With that said, I’m not in line to get a Covid vaccine anytime soon nor is anyone in my family. By the time it’s our turn already, we’ll (hopefully) get the J&J version soon.

    Prizer vaccine, anyone?

    4B173326-F183-48A9-B88B-17EB69332F88.jpeg
     
    Sir iAco and Godfather like this.
  18. Godfather

    Godfather PhilMUG Addict Member

    Joined:
    Jun 2, 2006
    Messages:
    4,395
    Likes Received:
    3,811
    Gender:
    Male
    Location:
    Here and There
    Ingat mga Sirs/Mam, nagstart na vaccination kahapon sa PGH.. yung kaibigan kong nurse nagpa vaccine kahapon... pagka inject sa kanya medyo okay naman sya... pero yung nag ddrive na sya pauwi parang nag blurred ang vision nya.. pagdating nya house, nahihilo na sya... tumawag agad sya sa vaccination center, sinabi nya yung mga nararamdaman nya. Pinababalik agad sya sa PGH, pero advise sa kanya magsama ng magddrive para sa kanya... pag dating na pagdating nya sa vaccination center, binigay sa kanya agad yung eyeglasses nya...naiwan nya pala. Pagsuot nya, lumiwanag na paningin nya........di nadin sya nahilo.
     
  19. ice

    ice PhilMUG Addict Member

    Joined:
    Dec 13, 2007
    Messages:
    10,053
    Likes Received:
    2,046
    Location:
    NCR
    Sir iAco likes this.
  20. Sir iAco

    Sir iAco PhilMUG Addict Member
    Supporter

    Joined:
    Jan 1, 2009
    Messages:
    1,695
    Likes Received:
    637
    Location:
    Faking Here
    Dr. Fauci has a stunningly simple way to explain how Johnson & Johnson's COVID-19 vaccine differs from Pfizer's and Moderna's shots
    Hilary Brueck
    Wed, March 3, 2021, 12:37 PM
    Dr. Fauci has a stunningly simple way to explain how Johnson & Johnson's COVID-19 vaccine differs from Pfizer's and Moderna's shots (yahoo.com)
    • There are now three COVID-19 vaccines authorized for use in the US.

    • Pfizer's and Moderna's are mRNA-based, while Johnson & Johnson's is an adenovirus.

    • Dr. Anthony Fauci explained how they differ but have the same "end game."

    • Visit the Business section of Insider for more stories.
    The US now has authorized three coronavirus vaccines: two mRNA options from Pfizer and Moderna, and one adenovirus shot from Johnson & Johnson.

    While it's true that Moderna's and Pfizer's shots were more effective overall than J&J's in trials, experts have stressed that all these vaccines share two very important statistics: zero hospitalizations and zero deaths among fully vaccinated trial participants.

    When asked which shot might provide people the best long-term protection from infection, including protection against worrisome virus variants like B.1.351, Florian Krammer, a leading virus expert, told Insider on Monday, "There's little that can be said, for now."

    We do already know there are key differences in the way these two types of vaccines work.

    During a White House briefing on Monday, President Joe Biden's chief medical advisor, Dr. Anthony Fauci, explained exactly how each shot takes effect.

    Shots from Pfizer and Moderna give the body genetic instruction manuals to safely learn how to fight the coronavirus
    [​IMG]
    Pfizer's mRNA-based COVID-19 vaccine. Pete Bannan/MediaNews Group/Daily Local News via Getty Images
    Pfizer's and Moderna's vaccines train the body to fight COVID-19 by injecting mRNA, or messenger RNA, into a person's deltoid, the rounded muscle that hugs the upper arm and shoulder.

    "The mRNA that's injected into the muscle codes for the spike protein," Fauci said.

    The coronavirus' spike protein is what allows the virus to latch on to and invade our cells. But the mRNA vaccines train our bodies to say, immunologically, "Not so fast."

    "The body sees that [protein] and makes an immune response against that, giving you the protection that has been shown with both of the mRNA vaccines," Fauci added.

    J&J inserts a harmless cold virus to do the same job
    [​IMG]
    Boxes of Johnson & Johnson's vaccine. Timothy Easley/AFP via Getty Images
    J&J's shot injects viral DNA, not mRNA. This is a key reason J&J's vaccine is so much easier to manufacture and to store in the fridge: The DNA inside is not as fragile as the single-stranded mRNA in Pfizer's and Moderna's shots.

    That DNA is encapsulated in a "harmless, non-replication-competent virus," Fauci said.

    That adenovirus, called Ad26, is a common cold virus that has had its illness-causing genes removed, so it can't get you sick.

    Once the vaccine is injected into a person's arm, the virus injects its DNA into cells, where it's copied into messenger RNA. That mRNA then codes for coronavirus spike proteins in the same way as Pfizer's or Moderna's shots.

    Both types of vaccines result in the same 'end game' for the virus
    [​IMG]
    Fauci in Washington, DC, on February 25. Saul Loeb /AFP via Getty Images
    The "ultimate end game" of adenovirus and mRNA COVID-19 vaccines is the same, Fauci said.

    "Both of the vaccines ultimately result in a spike protein in the right conformation that gives the body the opportunity to feel that this is the actual virus that it's seeing," he said.

    To be clear, he added, it's not the virus, "it's the protein."

    That prepares a vaccinated person's body to fight off a COVID-19 infection if the person comes into contact with the virus.

    Both the mRNA and the adenovirus vaccines appear to prevent the most severe COVID-19 infections very well: Pfizer's and Moderna's two-shot courses were more than 94% effective in their trials, while J&J's was 85% effective in preventing severe disease and death.

    Adenovirus vaccines like J&J's might give people a more robust form of immunity against viral variants, with antibody and T-cell responses. (mRNA vaccines may provide only more narrow antibody protection.) But that remains to be seen as more people get vaccinated and variants continue to spread.

    Either way, experts agree that all three authorized vaccines need to work in concert in order to blunt the spread of the virus across the US and to help end the pandemic.

    Read the original article on Business Insider

    Dr. Fauci has a stunningly simple way to explain how Johnson & Johnson's COVID-19 vaccine differs from Pfizer's and Moderna's shots (yahoo.com)

    [​IMG]
    Why Johnson & Johnson's COVID-19 vaccine will help in the fight to end the pandemic
    Tue, March 2, 2021, 4:24 PM

    On Feb. 27, the Johnson & Johnson COVID-19 vaccine was granted emergency use authorization by the Food and Drug Administration. It’s now the third vaccine approved in the U.S., joining those from Pfizer and Moderna. Yahoo News Medical Contributor Dr. Kavita Patel explains how the Johnson & Johnson vaccine differs and how it will help in the fight to end the coronavirus pandemic.

    [​IMG]
    Some of the first Johnson & Johnson vaccine doses given at Ohio State University
    Wed, March 3, 2021, 7:54 AM

    At Ohio State University those walking in to get vaccinated will be able to choose between Pfizer and Johnson & Johnson shots. CBS News spoke to one senior who was elated the Johnson & Johnson vaccine is now available because she has an allergy related to the Pfizer shot. David Begnaud reports.

    Dr. Fauci has a stunningly simple way to explain how Johnson & Johnson's COVID-19 vaccine differs from Pfizer's and Moderna's shots (yahoo.com)
     
    raypin likes this.

Share This Page

  • About PhilMUG

    Since the mid-1990s, PhilMUG (formerly the Philippine Macintosh Users Group) has grown to become not just the Philippines’ but one of the world’s foremost Apple user groups. Our online community brings together thousands of members from the Philippines and around the world for the latest news and discussions covering all Apple products and related hardware and software. Anyone can join PhilMUG, from newbies to experts, subject to our membership rules and guidelines.
  • Like us on Facebook

  • Buy us a beer!

    The staff works very hard to make sure that PhilMUG is running 24/7. Care to buy us a beer or help out with our hosting fees? We'd really appreciate it!

    Donate to us!